Effect of “Ginseng” administration on the structural and ultrastructural changes produced by restraint stress in the liver cells of albino rats

This study aimed to assess the antistress effects of “Ginseng” in cases of chronic restraint stress by studying the structural and ultrastructural changes of the liver cells. Fifteen adult male albino rats were used. They were divided equally into 3 groups: control, stress and stress/Ginseng groups. Restraint stress was applied to both stress and stress/Ginseng groups 4 hours every other day for 4 weeks.15 mg Ginseng/kg/ was given to stress /Ginseng group every other day for 4weeks. Examination of liver specimens processed for both light and electron microscopic study revealed that chronic restraint stress causes fatty degeneration which may proceed to necrosis of the liver cells. A hepatoprotectective effect of ginseng was observed.